Clinical Skin Retinol + Peptide Refining Serum | Gentle Retinol

A retinol serum built to be used every night, chosen by Professor Caitriona Ryan

The Retinol + Peptide Refining Serum is Professor Caitriona Ryan's retinol of choice, and the evening step in her own anti-ageing routine. It pairs pure retinol with bakuchiol, a gentler plant based retinol alternative, so you get the renewal of a retinoid with less of the redness and flaking that makes most people stop.

• Pure retinol for skin renewal
• Bakuchiol, a gentler retinol alternative
• Palmitoyl Tripeptide 38, a peptide that supports the skin's structure
• Niacinamide and allantoin to keep skin calm

Why the gentle approach matters

Retinoids are among the most studied topical ingredients for ageing skin. Their biggest weakness is not how well they work, it is how many people give up on them in the first few weeks because of dryness and irritation.

The best retinoid is the one your skin tolerates every night. This serum balances retinol with soothing ingredients so consistency becomes realistic.

Who it is for

• Fine lines and uneven texture
• Uneven looking skin tone
• Anyone who has found other retinols too harsh

Not suitable if you are pregnant, breastfeeding or planning a pregnancy.

How to use

1. Cleanse and pat skin dry in the evening.
2. Smooth a small amount over the face, neck and chest with your fingertips.
3. Follow with your moisturiser.

Start every other night. Some mild redness or peeling can happen as your skin adjusts. Once it has, nightly use is recommended. Always wear a broad spectrum SPF 30 or higher during the day.

Size: 30ml

What is in it

• Retinol: encourages cell renewal and a resilient skin structure.
• Bakuchiol: a plant based ingredient that works alongside retinol with less irritation.
• Palmitoyl Tripeptide 38: a messenger peptide shown to stimulate six major components of the skin's support structure.
• Niacinamide: helps protect skin from oxidative stress caused by pollution.
• Allantoin: hydrates and soothes.

Build the full routine

This serum is the evening step in Professor Caitriona Ryan's Anti-Ageing Bundle, her own five step routine with cleanser, toner, barrier cream and mineral SPF 50. Save €58 when you buy them together.

Frequently asked questions

Is it suitable for retinol beginners?

Yes. Start every other night and build up to nightly use as your skin adjusts.

What does bakuchiol do?

Bakuchiol is a plant based ingredient that behaves in a similar way to retinol but is gentler on the skin. Here it works alongside pure retinol to reduce irritation.

Can I use it in the morning?

Use it in the evening. Retinol is best applied at night, followed by SPF every morning.

Can I use it with vitamin C?

Yes. Use vitamin C in the morning and the retinol serum at night.

Can I use it while pregnant?

No. It is not suitable during pregnancy, while breastfeeding or if you are planning a pregnancy.